Coronary Artery Disease and Cardiomyopathy
One reason for the poor prognosis in patients with diabetes after myocardial infarction is the increased susceptibility to develop heart failure. Diabetic men have more than twice the frequency of heart failure than nondiabetic cohorts, while diabetic women have a 5-fold increased risk of developing heart failure. This excessive risk of heart failure persists despite
Pathophysiology/Risk Factors The increased cardiovascular event rate in diabetes is partially due to independent contributions of the other major cardiovascular risk factors. Most patients with type 2 DM have the insulin resistance syndrome, also known as the metabolic syndrome, characterized by clustering of metabolic risk factors including hypertension, hyperinsulinemia, glucose intolerance, and dyslipidemia.Diabetes is also
Cardiovascular disease (CVD) is the leading cause of death in patients with type 2 diabetes. Epidemiological studies have shown that diabetes mellitus is a potent independent risk factor for cardiovascular disease. It has been recognized for several decades that diabetic patients have a 2- to 3-fold higher risk for CVD than their nondiabetic counterparts.