Prevention of Microvascular Complications of Diabetes Mellitus

Hyperglycemia in both type 1 and type 2 diabetes appears to set off a complex network of intracellular signaling mechanisms that lead to the characteristic microvascular complications of diabetes – retinopathy, nephropathy, and neuropathy. Chronic hyperglycemia (as measured by Hgb A1c) is clearly the main common etiologic factor behind these complications, and thus treatment methods